Nearly all research in neurofeedback since the 1960s has focused on training voluntary control over EEG constructs. By contrast, EEG state discrimination training focuses on awareness of subjective correlates of EEG states. This study presents the first successful replication of EEG alpha state discrimination first reported by Kamiya . A 150-s baseline was recorded in 106 participants. During the task, low triggered a prompt. Participants indicated “high” or “low” with a keypress response and received immediate feedback. Seventy-five percent of participants (...) achieved significant discrimination within nine sessions, with a significant learning curve effect. Performance was significantly related to physical properties of the EEG signal, including magnitude, duration, and absolute vs. relative amplitude. These results are consistent with a conceptualization of EEG state discrimination as a sensory modality, although it is also intricately related to voluntary control of these states. (shrink)

The Monographs produced by the International Agency for Research on Cancer (IARC) apply rigorous procedures for the scientific review and evaluation of carcinogenic hazards by independent experts. The Preamble to the IARC Monographs, which outlines these procedures, was updated in 2019, following recommendations of a 2018 expert Advisory Group. This article presents the key features of the updated Preamble, a major milestone that will enable IARC to take advantage of recent scientific and procedural advances made during the 12 years since (...) the last Preamble amendments. The updated Preamble formalizes important developments already being pioneered in the Monographs Programme. These developments were taken forward in a clarified and strengthened process for identifying, reviewing, evaluating and integrating evidence to identify causes of human cancer. The advancements adopted include strengthening of systematic review methodologies; greater emphasis on mechanistic evidence, based on key characteristics of carcinogens; greater consideration of quality and informativeness in the critical evaluation of epidemiological studies, including their exposure assessment methods; improved harmonization of evaluation criteria for the different evidence streams; and a single-step process of integrating evidence on cancer in humans, cancer in experimental animals and mechanisms for reaching overall evaluations. In all, the updated Preamble underpins a stronger and more transparent method for the identification of carcinogenic hazards, the essential first step in cancer prevention. (shrink)

This paper involves one crucial assumption; namely, that the statistical predictions of quantum mechanics for Bell's variant of the EPR experiment will continue to be verified as detector efficiencies are improved and the need for coincidence counters is eliminated. This assumption entails that any hidden-variables theory for quantum mechanics must violate Bell's inequality--the inequality derived in Bell (1964). It is shown here that four locality conditions are involved in the derivation of Bell's inequality; and that a violation of any of (...) the four locality conditions will either entail the existence of superluminal influences or the existence of superluminal signals (superluminal influences that can be used to transmit information), if conspiratorial theories can be ruled out. The attempts so far to rule out conspiratorial theories are all found to be rather dubious, but there are other considerations developed here that rule them out convincingly. Finally, it is demonstrated that violations of each of the four locality conditions can be used to transmit information superluminally, if certain auxiliary conditions are satisfied. This is of particular interest because one of these conditions corresponds to a condition dubbed "completeness" by Jon Jarrett. Jarrett and others have suggested that violations of completeness cannot be used to send information superluminally. Demonstrating otherwise is, perhaps, the most significant result obtained in this paper. (shrink)

No articulation of `historical thinking' has been as influential as Sam Wineburg's position, according to which historical thinking is, fundamentally, the recognition of the ways in which the past is different than the present. Wineburg argues, further, that achieving that state is `unnatural.' This paper critiques both of these claims, arguing instead that we should replace a generic conception of historical thinking with one that is much more rooted in the specific practice of the discipline. It is surely necessary for (...) students to learn this practice, but it is not unnatural. Instead, learning to think historically is learning to speak the language of the discipline that we call ‘history.’. (shrink)

Abstract Scholars find that political elites are badly polarized over a large range of policy issues, but they tend to agree that the mass public is much more ambivalent. The abortion war in particular is regarded as one in which millions of ambivalent citizens are caught in the crossfire of polarized activists. Yet even abortion activists struggle to escape the very ambivalent sentiments that plague ordinary Americans. These common sentiments even exert a moderating influence on both movements in ways that (...) are consistent with the preferences of the American public. They also suggest that liberalism may be mired in permanent conflict and ambivalence over the scope of basic human rights. (shrink)

Talisse and Maloney seem to think that professors, not ordinary citizens, are the key to a more deliberative democracy. Yet these professors fail to appreciate the reasonableness of the pro‐life activists and thinkers they disagree with. For example, they falsely charge even the most deliberative groups with resurrecting an obsolete debate and framing conversations in a fallacious way. They further place an unreasonable justificatory burden on pro‐life activists and hold them culpable for framing the debate around the ontology of the (...) embryo . In drawing such a hard line between academics and activists, they also miss what has been an unavoidable partnership between academics and social movements in our imperfect deliberative republic. (shrink)

This paper takes up and provides three answers to the question “Why study philosophy?” Beginning with a discussion of why this question has been ignored in literature pertaining to the teaching of philosophy, the paper turns to an analysis of what it means to ask about the importance of philosophy, pointing out that the question is ambiguous with other questions like “why should so-and-so study philosophy” or “why does so-and-so study philosophy.” The author then provides three answers that are similar (...) to those provided by Hume: one should study philosophy because it may contribute to the entertainment, instruction, and reformation of mankind. The paper argues for the superiority of these answers over traditional responses and points to the importance of this question in teaching philosophy. (shrink)

Social roles theorists claim that differences between the sexes are of limited consequence. Such misperceptions lead to misunderstanding the important role of sexual selection in explaining phenotypic differences both between species and within humans. Countering these claims, we explain how sexual dimorphism in humans affect expressions of artistic display and patterns of male and female aggression across the ovulatory cycle.

MORE THAN MOST PHILOSOPHERS, Spinoza needed a coherent and sophisticated set of views on the nature of possibility: many of his most important philosophical positions and arguments depended on it. As one example, take Ethics IP33. This Proposition—among the most famous of the Ethics— states, “Things could have been produced by God in no other way, and in no other order than they have been produced.” In a salutary attempt to clarify the meaning of IP33 et relata, Spinoza adds in (...) the first Scholium to IP33 that “by these propositions I have shown more clearly than the noon light that there is absolutely nothing in things on account of which they can be called contingent.” Now, such assertions were bound to give rise to numerous objections and Spinoza knew it. To meet these objections, he immediately proceeds to one of the most powerful: namely, are there not things that actually have been “produced by God” that need not have been “produced by God?” And would it not make sense to call these things “contingent or possible?” In reply, Spinoza reinterprets the concept of possibility. We call existing things “contingent” “only because of a defect of our knowledge.” There are, he continues, two types of deficiency that lead us to regard existing things as “contingent or possible”: either we do not know “that the thing’s essence involves a contradiction” or we do know that the thing’s essence does not involve a contradiction but we do not know enough about the “order of causes” to affirm anything “certainly about its existence.”. (shrink)

ABSTRACT The media's attentive vigil over America's most militant and outrageous activists in the abortion wars has obscured a massive but quiet effort on the part of evangelicals to engage their opponents in exemplary deliberative discussions about bioethics. For a variety of reasons, activists in the pro‐life movement are more committed to carving out civic spaces for such dialogue than are their pro‐choice counterparts. This discrepancy invites investigation into the forces that promote and constrain political movements' interest in deliberation, as (...) well as highlighting the undeniable limits to deliberative ideals. (shrink)

Donald Trump’s victory depended on the defection of hundreds of longstanding Democratic communities. Trump appealed to these communities partly because he behaves like some of their most beloved politicians. Like the president, these politicians are brazen, thin skinned, nepotistic, and offer an older, boss-centered vision of politics. Trump—the anti-establishment outsider—appealed to voters in these communities because he resembles the local insiders. This appeal widens an old fault line inside the Democratic Party.

According to the ‘fact-plus-value’ model of pathology propounded by K. W. M. Fulford, ‘disease’ is a value term that ought to reflect a ‘balance of values’ stemming from patients and doctors and other ‘stakeholders’ in medical nosology. In the present article I take issue with his linguistic-analytical arguments for why pathological status must be relative to such a kind of medico-ethical normativity. Fulford is right to point out that Boorse and other naturalists are compelled to utilize evaluative terminology when they (...) characterize the nature of diseases and biological dysfunctions. But the relevant ‘biofunctional judgements’ are no less factual and empirical for that. While it is indeed evaluative to say that biological dysfunctions involve failures to execute naturally selected functions, such judgments are not bound to entail anything about what is good or bad for us, and what should be treated or not. In the last part of the paper I ruminate briefly on the relationship between ‘biological evaluationism’, on my construal, and descriptions of ‘causal biology’. As I note in my conclusion, a strict bioevaluative concept of disease can be valid for every species on earth, and thus be of particular usefulness in general biological contexts. (shrink)

Critics of attention-deficit/hyperactivity disorder (ADHD) have repeatedly argued that there is no proof for the condition being symptomatic of an organic brain disease and that the current "ADHD epidemic" is an expression of medicalization. To this, the supporters of ADHD can retort that the condition is only defined as a mental disorder and not a physical disease. As such, ADHD needs only be a harmful mental dysfunction, which, like other genuine disorders, can have a complex and obscure etiology. This article (...) argues that such a line of argument fails to save ADHD as a valid diagnostic category. Given the general diagnostic logic of the DSM-IV and how ADHD has been defined in terms of everyday (male) child behaviors, there are compelling grounds to disbelieve that ADHD can be a true medical syndrome united by some type of harmful dysfunction. Indeed, strong logical and empirical reasons will be adduced to show that people may qualify for ADHD diagnosis without suffering from any type of underlying pathology. (shrink)

A collection of essays on rationality - its scope, its limitations and its failures.

A normative Bayesian theory of deliberation and judgement requires a procedure for merging the evidence of a collection of agents. In order to provide such a procedure, one needs to ask what the evidence is that grounds Bayesian probabilities. After finding fault with several views on the nature of evidence (the views that evidence is knowledge; that evidence is whatever is fully believed; that evidence is observationally set credence; that evidence is information), it is argued that evidence is whatever is (...) rationally taken for granted. This view is shown to have consequences for an account of merging evidence, and it is argued that standard axioms for merging need to be altered somewhat. (shrink)

Del Giudice addresses a complex and pertinent theoretical issue: the evolutionary adaptiveness of sex differences in attachment styles in relation to life history strategy. Although we applaud Del Giudice for calling attention to the problem, we regret that he does not sufficiently specify how attachment styles serve as an integral part of a coordinate life history strategy for either sex.

We use variation in corruption convictions across judicial districts in the US to examine the relationship between political corruption and risk-taking of public firms. Firms headquartered in regions with high levels of political corruption have lower total risk and lower idiosyncratic risk on average. Further analysis shows that corruption tends to encourage firms to pursue risk-decreasing investments, lower the riskiness of their operations, and decrease asset liquidity. While managerial ownership is intended to align the interests of managers and shareholders, the (...) presence of corruption appears to encourage undiversified managers to decrease risk-taking. Our evidence is consistent with agency theory and the asset-shielding argument that political corruption discourages managers from taking risks that expose firms to expropriation by politicians, resulting in suboptimal corporate policies. (shrink)

Casgevy, the world’s first approved CRISPR-based cell therapy, has been priced at $2.2 million per patient. Although this hefty price tag was widely anticipated, the extremely high cost of this and other cell and gene therapies poses a major ethical issue in terms of equitable access and global health. In this Perspective, we argue that lowering the prices of future CRISPR therapies is an urgent ethical imperative. Although we focus on Casgevy as a case study, much of our analysis can (...) be extrapolated to the controversies over affordable access to other gene and cell therapies. First, we explain why this first-of-its-kind CRISPR therapy might be so expensive. We then analyze the ethical issues of equity and global health of early CRISPR treatments. Next, we discuss potential solutions to lower the prices of CRISPR gene therapies. We conclude that the approval of CRISPR transforms our obligations of justice and compels us to bring future gene therapies to the maximum possible number of patients with serious genetic diseases at affordable prices. (shrink)

The essays in this volume, first published in 1986, examine the philosophical foundations of social choice theory. This field, a modern and sophisticated outgrowth of welfare economics, is best known for a series of impossibility theorems, of which the first and most crucial was proved by Kenneth Arrow in 1950. That has often been taken to show the impossibility of democracy as a procedure for making collective decisions. However, this interpretation is challenged by several of the contributors here. Other central (...) issues discussed in the volume include the possibility of making interpersonal comparisons of utility, the question of whether all preferences are equally to be valued, and the normative individualism underlying the theoretical tradition. Criticisms of social choice theory are advanced and suggestions for alternative approaches are developed. (shrink)

Badiou's Deleuze presents the first thorough analysis of one of the most significant encounters in contemporary thought: Alain Badiou's summary interpretation and rejection of the philosophy of Gilles Deleuze. Badiou's reading of Deleuze is largely laid out in his provocative book, Deleuze: The Clamor of Being, a highly influential work of considerable power. Badiou's Deleuze presents a detailed examination of Badiou's reading and argues that, whilst it fails to do justice to the Deleuzean project, it invites us to reconsider what (...) Deleuze's philosophy amounts to, and to reassess Deleuze's power to address the ultimate concerns of philosophy. Badiou's Deleuze analyses the differing metaphysics of two of the most influential of recent continental philosophers, whose divergent views have helped to shape much contemporary thought. (shrink)

This article discusses the effects of the OECD Convention on Combating the Bribery of Foreign Public Officials, which was signed in 1997 and is due to be implemented by the signatory nation‐states this year. The Convention represents the expansion of legal measures to combat the bribery of foreign public officials by individuals or corporations, and it has been accompanied by the Organisation of American States’ Convention Against Corruption. Previously the Foreign Corrupt Practices Act , which applied only to United States (...) individuals or corporations, ‘stood alone in the world as a legal barrier to transnational bribery’ . This article proceeds in stages to evaluate implications of the Convention. Firstly the Convention is placed in the context of the increased focus on transnational business bribery in recent years. Second, the main points of the Convention are outlined. Third, the issues and problems posed by the Convention for business are discussed. Finally some themes regarding enforcement by the relevant authorities are outlined. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Plot Taxonomies and IntentionalityJon AdamsEver popular among the various topics occupying non-academic conversations about literature—such as the identity of the real author of the plays attributed to "Shakespeare"—is the notion that there exists only a finite number of storylines, and that all the stories we know are only ever complications or rehearsals of these few, elementary plots. What is the status of that claim? The issue gains a renewed (...) relevance in light of literary criticism's recent interest in the possibilities of employing evolutionary psychology as a means of naturalising literary study, but interest in plot taxonomies stretches a long way back. Why might we seek to categorise plots into a finite taxonomy? And what are the implications of the claim if true?Organising literature into any classificatory scheme is an attempt to achieve something like the coherence that the natural sciences have achieved—in chemistry and physics with the composition of the periodic table, and in biology with Linnaean classification. Much of science's epistemic prestige is rooted in the enormous success with which they have organised and categorised their subject of study. In searching for mechanism and pattern, the natural sciences proceed confidently from the belief that those mechanisms and patterns exist to be discovered, and that (relatively) simple rules underlie the manifest complexity of natural phenomena.Unfortunately, the study of literary fiction has no such security. There are two senses here in which we can talk of literature being patterned. At the micro-level, we have the question of whether individual works can be thought of as internally patterned. Usually, this type of patterning is easy enough to establish and recognise, and something the author is (or ought to be) in a good position to control. But, of course, internal [End Page 102] structures are not always conspicuous, and readers faced with an overtly complex text, like Pound's Cantos, or Finnegans Wake, have no guarantee that there is sense to be made of it. Surface complexity may shield a profound and subtle architecture, or the work may be as unstructured, fragmentary, and chaotic as it initially appears. A frustrated Wayne C. Booth draws attention to the problem: "One can't be sure that Finnegans Wake is not a great novel; perhaps someday readers will discover that the complex structure they now dream of and quarrel about is a realizable structure, an experienced structure. I doubt it, but it may happen. Until then, each new intricacy discovered... reveals precisely nothing more than that: a new intricacy."1 What's missing is a conceptual centre around which overall coherence might be achieved from what had seemed to be unconnected parts. Even so, if this sort of centre cannot be found in the individual work, it may yet obtain between works. In other words, The Cantos or Finnegans Wake may yet occupy nodal roles in a larger system, within which they acquire a previously unrecognized unity and order. This type of organization is something the individual author is obviously in a much less suitable position to control. Nonetheless, mapping out this larger, macro-level order is a task that literary criticism might want to take on. There is the example Borges uses of how Kafka's work retrospectively confers a familial similarity upon previously unconnected works. The quality of being "Kafkaesque" is the only thing common to the pieces, but was not apparent (or rather—the paradox that excites Borges—did not exist) prior to Kafka's writing.2 This is the second sense in which literature might be thought of as patterned; that is, not within works, but across them. On the larger scale, is it possible that literature as a whole could be understood as patterned?The notion that literature can be understood "as a whole," and its corollary, that a literature so understood would submit to taxonomical classification, is an enduring one. Anthropologists and art historians have long acknowledged that there appear to be recurring themes, motifs, and commonalities across world cultures, and consequently, commonalities among the narratives those cultures construct and consume. Cataloguing these similarities has produced a variety of classificatory systems.In the mid-nineteenth century, German scholar Adolf... (shrink)

Law plays a critical role in all stages of a public health emergency, including planning, response, and recovery. Public health emergencies introduce health concerns at the population level through, for example, the emergence of a novel infectious disease. In the United States, at the federal, state, and local levels, laws provide an infrastructure for public health emergency preparedness and response efforts: they grant the government the ability to officially declare an emergency, authorize responders to act, and facilitate interjurisdictional coordination. Law (...) is perhaps most visible during an emergency when the president or a state's governor issues a disaster declaration establishing the temporal and geographic parameters for the response and making financial and other resources available. This legal authority has increasingly been used during the last decade. (shrink)

Alfred Schutz in his phenomenological studies on the social world, has systematically analyzed the nature of social relationships between individuals, and has arrived at an originating point involving intersubjectivity. This point is described by what he calls the Pure We-relationship. Comparison of Schutz's analysis of the Pure We relationship with Buber's description of his personal experience of intersubjectivity, i.e., the l-Thou relationship, reveals a remarkable convergence. For instance, fundamental to both Schutz and Buber are the notions that intersubjectivity is tied (...) to the lived presence of the self with the other (i.e., sharing of time in the stream of duration), and that the 'content' of this 'experience' is related to the being of the other. These interesting features in the works of Schutz and Buber are described by showing the similarity between the Pure We and I-Thou relationships. (shrink)

The multiple realizability thesis (MRT) is an important philosophical and psychological concept. It says any mental state can be constructed by multiple realizability (MR), meaning in many distinct ways from different physical parts. The goal of our study is to find if the MRT applies to the mental state of consciousness among animals. Many things have been written about MRT but the ones most applicable to animal consciousness are by Shapiro in a 2004 book called The Mind Incarnate and by (...) Polger and Shapiro in their 2016 work, The Multiple Realization Book. Standard, classical MRT has been around since 1967 and it says that a mental state can havevery manydifferent physical realizations, in a nearly unlimited manner. To the contrary, Shapiro’s book reasoned that physical, physiological, and historical constraints force mental traits to evolve in just a few, limited directions, which is seen as convergent evolution of the associated neural traits in different animal lineages. This is his mental constraint thesis (MCT). We examined the evolution of consciousness in animals and found that it arose independently in just three animal clades—vertebrates, arthropods, and cephalopod mollusks—all of which share many consciousness-associated traits: elaborate sensory organs and brains, high capacity for memory, directed mobility, etc. These three constrained, convergently evolved routes to consciousness fit Shapiro’s original MCT. More recently, Polger and Shapiro’s book presented much the same thesis but changed its name from MCT to a “modest identity thesis.” Furthermore, they argued against almost all the classically offered instances of MR in animal evolution, especially against the evidence of neural plasticity and the differently expanded cerebrums of mammals and birds. In contrast, we argue that some of these classical examples of MR are indeed valid and that Shapiro’s original MCT correction of MRT is the better account of the evolution of consciousness in animal clades. And we still agree that constraints and convergence refute the standard, nearly unconstrained, MRT. (shrink)

Offers a postmodern theory of knowledge based on an ecological worldview that stresses real relations and the pervasiveness of values.

Over the past few decades, significant research efforts have been devoted to establishing a relationship between African Philosophies of Education (APE) and School Leadership (SL). Such efforts have revealed how important African Union Philosophies of Education (AUPE) have been, or could be, in shaping School Leadership (SL) policies and practices. To achieve the above, this paper reviews contemporary literature on African Indigenous Education (AIE) and school leadership (SL) research. A descriptive and analytical interpretive approach is used to understand the methodological (...) approaches used by existing research to redress an underdeveloped engagement with theory and practical claims from other studies. In so doing, we identify the salient values of these African philosophies of Education, bringing out their qualities as well as their limitations, and discussing ways in which they could be incorporated into the contemporary field of School Leadership (SL). This study proposes an epistemic theoretical framework to guide the delivery of African Philosophies of Education (APE) in School Leadership (SL) practice. Such a framework would be developed as part of the de-colonisation epistemic movement within the global south, noting that this movement has yet to be significantly felt in the field of educational leadership. (shrink)

The acquisition of genetic information (GI) confronts both the affected individuals and healthcare providers with difficult, ambivalent decisions. Genetic responsibility (GR) has become a key concept in both ethical and socioempirical literature addressing how and by whom decision-making with respect to the morality of GI is approached. However, despite its prominence, the precise meaning of the concept of GR remains vague. Therefore, we conducted a systematic literature review on the usage of the concept of GR in qualitative, socioempirical studies, to (...) identify the main interpretations and to provide conceptual clarification. The review identified 75 studies with primarily an Anglo-American setting. The studies focused on several agents: the individual, the family, the parent, the healthcare professional, and the institution and refer to the concept of GR on the basis of either a rational/principle-oriented approach or an affective/relational approach. A subtype of the rational/principle-oriented approach is the reactive approach. The review shows how the concept of GR is useful for analyzing and theorizing about socioempirical findings within qualitative socioempirical studies and also reveals conceptual deficits in terms of insufficient theoretical accuracy and heterogeneity, and in the rarity of reflection on cultural variance. The vagueness and multiplicity of meanings for GR in socioempirical studies can be avoided by more normative-theoretical explication of the underlying premises. This would provide a higher degree of differentiation of empirical findings. Thereby, the complex findings associated with the individual and social implications of genetic testing in empirical studies can be better addressed from a theoretical point of view and can subsequently have a stronger impact on normative and policy debates. (shrink)

Using the right to die and the United States Supreme Court case of Cruzan v. Director, Missouri Department of Health as exemplars, this article explores the notion of third-order decisionmaking. If first order decisionmaking is about what should happen, and second-order decisionmaking is about who should decide what should happen, then third-order decisionmaking is about who should decide who decides. This turns out to be an apt characterization of constitutionalism, which is centrally concerned with the allocation of responsibility for making (...) decisions about the allocation of responsibility. Deference to erroneous second-order decisions, as in the Cruzan case itself, may merely be an example of this central feature of constitutionalism. Keywords: constitutionalism, Cruzan case, right-to-die, rules CiteULike Connotea Del.icio.us What's this? (shrink)